Cnidilin

SKU: orb1684978

Description

Cnidilin, a coumarin isolated from Angelica dahurica, exhibits high blood-brain barrier permeability, highlighting its pharmacokinetic potential for central nervous system (CNS) disorder research. It is investigated in vitro and in vivo for its neuropharmacological activities relevant to conditions like ischemia and pain.

Key Properties

• CAS Number: 14348-22-2
• MW: 300.31
• Purity: 99.76% (May vary between batches)
• Formula: C₁₇H₁₆O₅
• SMILES: O(CC=C(C)C)C=1C2=C(C(OC)=C3C1C=CO3)OC(=O)C=C2
• Target: Others

Bioactivity

• In Vitro:
  Cnidilin (10、20 μg/mL) percent inhibition of nitric oxide synthase expression at 53.7 % in lipopolysaccharide (1 ug/mL) stimulated RAW 264.7 cells at 20 ug/mL.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cnidilin, Knidilin, P-gp

Compound Identifiers

PubChem CID

821449