Clozapine-d3

SKU: orb2299705

Description

Clozapine-d3 (CAS 5786-21-0) is a deuterated analog of the atypical antipsychotic clozapine. This tricyclic dibenzodiazepine exhibits a unique receptor profile, acting as a potent serotonin 5-HT2A/2C antagonist with weak D2 dopaminergic activity. It is widely used as an internal standard in LC-MS/MS for pharmacokinetic studies in both in vivo and in vitro research on schizophrenia and receptor pharmacology.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1215691-72-7
• MW: 329.84
• Formula: C₁₈H₁₆D₃ClN₄
• SMILES: C([2H])([2H])([2H])N1CCN(C2C3C(=CC=CC=3)NC3C=CC(Cl)=CC=3N=2)CC1
• Target: AChR,Adrenergic Receptor,5-HT Receptor,Dopamine Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135891297