Clindamycin-d3 hydrochloride

SKU: orb3138970

Description

Clindamycin-d3 (hydrochloride) is the deuterated form of Clindamycin. Clindamycin is an orally active, broad-spectrum lincosamide antibiotic that efficiently inhibits bacterial protein synthesis. It can suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Resistance to Clindamycin arises from the enzymatic methylation of the antibiotic binding site on the 50S ribosomal subunit (23S rRNA). It also reduces the production of leukocidin (PVL), toxic shock syndrome toxin-1 (TSST-1), and α-hemolysin (Hla). Additionally, Clindamycin is utilized in malaria research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1356933-72-6
• MW: 464.46
• Formula: C₁₈H₃₄Cl₂N₂O₅S
• SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C([2H])([2H])[2H])([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[H].Cl
• Target: Parasite,Antibacterial,Antibiotic

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Parasite,Antibacterial,Antibiotic