Cleaved-Caspase 6 p18 Antibody

• Catalog Number: orb1730715
• Category: Antibodies
• Description: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, IHC, WB
• Reactivity: Human, Rat
• Isotype: Rabbit IgG
• Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: Calculated MW: 33 kDa; Observed MW: 20,35 kDa
• Entrez: 839
• UniProt ID: P55212
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease
• Note: For research use only
• Expiration Date: 12 months from date of receipt.