cis MZ 1

SKU: orb1690066

Description

cis MZ 1 (CAS 1797406-69-9) serves as a negative control for the PROTAC degrader MZ 1, as it lacks VHL binding affinity and thus does not degrade BRD4. It is a critical tool for validating on-target degradation effects in both cellular and biochemical PROTAC mechanism studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1797406-72-4
• MW: 1002.64
• Purity: 99.23% (May vary between batches)
• Formula: C₄₉H₆₀ClN₉O₈S₂
• SMILES: CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@H](O)C4)C(C)(C)C)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C
• Target: PROTACs
• Solubility: DMSO:80 mg/mL (79.79 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cis-MZ 1, cis-MZ1, cis MZ 1, cis MZ1

Compound Identifiers

PubChem CID

124201820