Chromomycin A3

SKU: orb1710051

Description

Chromomycin A3 is a Streptomyces-derived antibiotic that binds GC-rich DNA sequences with divalent cations, blocking replication and transcription. It serves as a fluorescent DNA stain in molecular biology and exhibits anticancer activity in research models for various cancers, including lung adenocarcinoma and melanoma.

Research Area

Cell Biology

Key Properties

• CAS Number: 7059-24-7
• MW: 1183.3
• Purity: >98%
• Formula: C₅₇H₈₂O₂₆
• SMILES: O=C1C=2C(C[C@@]([C@@H](C([C@H]([C@@H](C)O)O)=O)OC)([C@@H]1O[C@H]3C[C@@H](O[C@H]4C[C@@H](O[C@H]5C[C@](C)(O)[C@@H](OC(C)=O)[C@H](C)O5)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)[H])=CC=6C(C2O)=C(O)C(C)=C(O[C@H]7C[C@@H](O[C@@H]8C[C@@H](O)[C@@H](OC)[C@@H](C)O8)[C@@H](OC(C)=O)[C@@H](C)O7)C6
• Target: DNA
• Solubility: Soluble in DMSO (up to 20 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aburamycin B; CMA3; NSC-58514

Compound Identifiers

PubChem CID

656673