Chlorhexidine hydrochloride

SKU: orb1225178

Description

Chlorhexidine dihydrochloride is an antibacterial, used as an antiseptic and for other applications.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3697-42-5
• MW: 578.38
• Purity: >98% (HPLC)
• Formula: C₂₂H₃₂Cl₄N₁₀
• SMILES: N=C(NC1=CC=C(Cl)C=C1)NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N.[H]Cl.[H]Cl
• Target: Antifection
• Solubility: DMSO: 100 mg/mL warmed (172.89 mM)

Bioactivity

• In Vivo:
  Animal model: Wistar rats. Dosage: 0.5 ml of 0.12% chlorhexidine digluconate. Administration: Oral. Result: Observed significant increase of DNA damage in leukocytes and oral mucosal cells.
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• In Vitro:
  Cell Viability Assay Cell line: S. aureus Concentration: 100 μM, 200 μM. Incubation time: 15 min, 30 min, 15 min, 60 min, 120 min, 240 min. Result: Showed a slow decrease during the first two hours and a sharp drop between 2 and 4 h of incubation at 200 μM.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CHX

Quick Database Links

Gene Symbol

Antifection