Cefodizime Sodium

SKU: orb1299197

Description

Cefodizime Sodium is a third-generation cephalosporin antibiotic with broad-spectrum activity. It is used in research for studying antibacterial mechanisms and efficacy in both in vitro susceptibility assays and in vivo infection models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 86329-79-5
• MW: 628.6
• Purity: 97.10% (May vary between batches)
• Formula: C₂₀H₁₈N₆Na₂O₇S₄
• SMILES: [Na+].[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSc3nc(C)c(CC([O-])=O)s3)=C(N2C1=O)C([O-])=O)c1csc(N)n1
• Target: Antibacterial,Antibiotic
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.36 mM);DMSO:100 mg/mL (159.08 mM)

Bioactivity

• In Vivo:
  A single dose of cefodizime 1 or 2 g is also useful in treating lower urinary tract infections, particularly uncomplicated infections, with a rate of clinical success of 72 to 88%. Urogenital gonorrhoea, whether caused by beta-lactamase producing or non-beta-lactamase producing Neisseria gonorrhoeae, is very effectively treated by single dose therapy with intramuscular cefodizime 0.25 to 1 g (virtually 100% cured). Preliminary data from a small number of patients indicate that cefodizime may also be useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gram-negative, Gram-positive, Inhibitor, inhibit, Antibiotic, broad, Bacterial, Cefodizime, Cefodizime Sodium, respiratory, spectrum, tracts, urinary

Compound Identifiers

PubChem CID

9852176