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CB1-IN-4

SKU: orb1226302

Description

CB1-IN-4 is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM; possess a low probability to cross BBB as a peripherally restricted CB1R antagonist, exhibits significant weight-loss efficacy in DIO mice, also displays 163 clean off-target profiles and potential for treating obesity and the related metabolic syndrome.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number1429239-98-4
MW751.6688
Purity>98% (HPLC)
FormulaC33H31Cl2F3N6O3S2
SMILESO=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(C#CC4=CC=C(C(F)(F)F)C=C4)S3)=C1CNS(=O)(N5CCCC5)=O)NN6CCCCC6
TargetCannabinoid Receptor
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DBPR211 | DBPR 211 | DBPR-211 | CB1-IN-1
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Protocol Information

CB1-IN-4 (orb1226302)

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Available Sizes

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2 mg
$ 320.00
5 mg
$ 530.00
10 mg
$ 750.00
25 mg
$ 1,210.00
50 mg
$ 1,680.00
100 mg
$ 2,260.00
500 mg
$ 4,510.00