CAY10471 Racemate

SKU: orb1299886

Description

CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective antagonist of the CRTH2/DP2 receptor, with significantly lower affinity for DP1 and TP receptors. It is widely used in research to investigate CRTH2-mediated allergic and inflammatory pathways in both cellular and animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 844639-57-2
• MW: 416.47
• Purity: 99.08% (May vary between batches)
• Formula: C₂₁H₂₁FN₂O₄S
• SMILES: [Na+].CN(C1CCc2c(C1)c1ccccc1n2CC([O-])=O)S(=O)(=O)c1ccc(F)cc1
• Target: GPCR,Prostaglandin Receptor
• Solubility: DMSO:150 mg/mL (360.17 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.6 mM)

Bioactivity

• Target IC50:
  CRTH2:0.6 nM(ki) |DP:1200 nM(ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CAY 10471, CAY10471, CAY-10471, CAY10471 Racemate, CAY-10471 Racemate, CRTh2 (DP2) receptor, Inhibitor, inhibit, Prostaglandin Receptor, ProstaglandinReceptor, TM 30089, TM30089, TM-30089, TM30089 Racemate

Compound Identifiers

PubChem CID

91885403