Cathepsin D and E FRET Substrate acetate

SKU: orb1303802

Description

This acetate-conjugated FRET substrate is a selective fluorogenic probe for cathepsins D and E, showing no activity against cathepsins B, H, or L. It is widely used in vitro for mechanistic enzymology studies and for monitoring protease activity in cellular models relevant to cancer and neurodegenerative disease research.

Research Area

Protein Biochemistry

Key Properties

• Target: Cysteine Protease
• Molecular Weight: 1802.04
• Purity: 95.63% (May vary between batches)
• Formula: C₈₆H₁₂₄N₂₂O₂₁
• SMILES: CC[C@@H]([C@H](NC([C@@H]1CCCN1C([C@@H](NC(CNC(C2=CC(OC3=C2C=CC(OC)=C3)=O)=O)=O)CCCCN)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N)=O)CCCNC(N)=N)=O)CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC5=CC=CC=C5)=O)CC6=CC=CC=C6)=O)CC(C)C)=O)C.CC(O)=O

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cysteine Protease, CysteineProtease, Cathepsin D and E FRET Substrate acetate (839730-93-7 Free base), Cathepsin D and E FRET Substrate acetate(839730 93 7 Free base), Cathepsin D and E FRET Substrate acetate(839730937 Free base), Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base), Cathepsin

Compound Identifiers

PubChem CID

168013034