Catestatin

SKU: orb1679293

Description

This small molecule is a selective, non-competitive antagonist of nicotinic acetylcholine receptors, potently inhibiting catecholamine secretion and cationic signaling (IC50 ~200-250 nM) while also promoting histamine release from mast cells. It is a valuable research tool for studying neurosecretion, autonomic neurotransmission, and mast cell function in both cellular and ex vivo experimental models.

Research Area

Neuroscience

Key Properties

• Target: AChR
• CAS Number: 142211-96-9
• MW: 2425.84
• Formula: C₁₀₇H₁₇₃N₃₇O₂₆S
• SMILES: C(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CO)=O)CCSC)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)CCCNC(=N)N)=O)(=O)N4[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)=O)CCC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16143960