Casopitant mesylate

SKU: orb1710148

Description

Casopitant mesylate (GW679769B) is a potent, selective, and orally bioavailable neurokinin 1 (NK1) receptor antagonist with good brain penetration. As a second-generation antiemetic, it is a valuable research tool for investigating the role of substance P in emesis, pain, and affective disorders in both in vitro and in vivo models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 414910-30-8
• MW: 712.72
• Formula: C₃₁H₃₉F₇N₄O₅S
• SMILES: CS(O)(=O)=O.C[C@@H](N(C)C(=O)N1CC[C@@H](C[C@@H]1c1ccc(F)cc1C)N1CCN(CC1)C(C)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
• Target: Neurokinin receptor,Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11686295