Capzimin

SKU: orb1710161

Description

Capzimin

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2084868-04-0
• MW: 628.81
• Purity: 98.31% (May vary between batches)
• Formula: C₃₀H₂₄N₆O₂S₄
• SMILES: O=C(NCCc1nccs1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCCc3nccs3)cccc2c1
• Target: Others,DUB,Proteasome
• Solubility: DMSO:50.1 mg/mL (79.67 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.18 mM)

Bioactivity

• In Vitro:
  In leukemia cells, Capzimin exhibits GI50s of 0.67 μM and 1 μM in SR and K562 cell lines. For non-small cell lung cancer, Capzimin exhibits a GI50 of 0.7 μM in NCI-H460. For breast cancer, Capzimin exhibits a GI50 of 1.0 μM in MCF7. Capzimin blocks cell growth and induces apoptosis in HCT116 cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Capzimin, Rpn11

Compound Identifiers

PubChem CID

126599606