Canfosfamide

SKU: orb1982177

Description

Canfosfamide (TLK-286) is a glutathione analog prodrug activated by glutathione S-transferase P1-1. Its activation releases an alkylating agent that induces apoptosis and inhibits DNA-PK kinase activity, supporting its investigation in cancer research across in vitro and in vivo studies.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 158382-37-7
• MW: 787.47
• Formula: C₂₆H₄₀Cl₄N₅O₁₀PS
• SMILES: P(N(CCCl)CCCl)(N(CCCl)CCCl)(OCCS(C[C@@H](C(N[C@@H](C(O)=O)C1=CC=CC=C1)=O)NC(CC[C@@H](C(O)=O)N)=O)(=O)=O)=O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5312109