Camizestrant

SKU: orb1709733

Description

Camizestrant

Research Area

Metabolism Research

Key Properties

• CAS Number: 2222844-89-3
• MW: 476.51
• Purity: 97.25%
• Formula: C₂₄H₂₈F₄N₆
• SMILES: C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ccc(NC2CN(CCCF)C2)cn1
• Target: Estrogen Receptor/ERR
• Solubility: DMSO:50 mg/mL (104.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.49 mM)

Bioactivity

• Target IC50:
  ERR:
• In Vivo:
  In human parental MCF7 mice xenograft, oral administration of Camizestrant (0.2-50 mg/kg) displays dose-dependent anti-tumor effects. Oral administration of Camizestrant (0.8-40 mg/kg) dose-dependently decreases the growth of the tumor.

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Camizestrant, ERR, Estrogen Receptor, estrogen receptor, EstrogenReceptor, Estrogen receptor antagonist 2

Compound Identifiers

PubChem CID

134453496