Caffeic Acid Phenethyl Ester

• Catalog Number: orb1300776
• Category: Small Molecules
• Description: Caffeic Acid Phenethyl Ester
• Purity: 99.18%
• MW: 284.31
• Biological Activity: Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
• CAS Number: [104594-70-9]
• Formula: C₁₇H₁₆O₄
• SMILES: Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
• Storage: -20°C
• Note: For research use only