Cabozantinib-d6

SKU: orb3138225

Description

Cabozantinib-d6 is the deuterated form of Cabozantinib. As a potent multi-receptor tyrosine kinase inhibitor, Cabozantinib targets VEGFR2, c-Met, Kit, Axl, and Flt3 with IC50 values of 0.035, 1.3, 4.6, 7, and 11.3 nM, respectively.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1802168-46-2
• MW: 507.54
• Formula: C₂₈H₂₄FN₃O₅
• SMILES: C(NC1=CC=C(OC=2C3=C(C=C(OC([2H])([2H])[2H])C(OC([2H])([2H])[2H])=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4
• Target: c-Kit,TAM Receptor,VEGFR,c-Met/HGFR,FLT,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

c-Kit,TAM Receptor,VEGFR,c-Met/HGFR,FLT,Apoptosis