c-Kit-IN-14

SKU: orb3173995

Description

c-Kit-IN-14 (Compound 1) is a c-kit kinase inhibitor. It effectively inhibits the phosphorylation of wild-type c-kit, with an IC50 value of 0.4 nM for pKIT. Additionally, c-Kit-IN-14 inhibits Exon 11 KIT with an IC50 value of 0.4 nM. This compound is applicable in the research of mast cell-mediated diseases, such as urticaria.

Key Properties

• CAS Number: 3041025-49-1
• MW: 565.99
• Formula: C₂₆H₂₅ClFN₉O₃
• SMILES: C(NC1=CC(=C(F)C=C1Cl)C2=NN(N=N2)C3CC3)(=O)C4=C5N(C=CC(=C5)C6=CN(C[C@H](COC)O)N=C6C)N=C4
• Target: c-Kit

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

c-Kit