C-82

SKU: orb1309889

Description

C-82

Research Area

Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1422253-37-9
• MW: 578.66
• Purity: 98.86%
• Formula: C₃₃H₃₄N₆O₄
• SMILES: [H][C@]12[C@H](C)N(Cc3cccc4cccnc34)C(=O)[C@H](Cc3ccc(O)cc3)N1C(=O)CN(C)N2C(=O)NCc1ccccc1
• Target: Wnt/beta-catenin,Epigenetic Reader Domain
• Solubility: DMSO:55 mg/mL (95.05 mM)

Bioactivity

• In Vivo:
  PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo, and pre-clinical studies have shown a very acceptable toxicity profile.
• In Vitro:
  C-82 inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

C82, C-82, CBP, CBP/β-catenin, bcatenin, C 82, beta-catenin, betacatenin, Epigenetic Reader Domain, EpigeneticReaderDomain, βcatenin, β-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin

Compound Identifiers

PubChem CID

73602848