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Bucindolol hydrochloride

SKU: orb1700944

Description

Bucindolol is a fourth-generation beta-blocker that has demonstrated efficacy in preventing new-onset atrial fibrillation. Research indicates its therapeutic response is influenced by β₁ and α(2c) adrenergic receptor polymorphisms, with β₁389 Arg homozygotes showing a 74% enhanced effect. This small molecule is utilized in cardiovascular research, including studies on arrhythmia mechanisms and pharmacogenetics.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number70369-47-0
MW399.91
FormulaC22H26ClN3O2
SMILESCl.N#CC=1C=CC=CC1OCC(O)CNC(C)(C)CC2=CNC=3C=CC=CC32
TargetAdrenergic Receptor,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Bucindolol hydrochloride (orb1700944)

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