BRD9185

SKU: orb1707513

Description

BRD9185 is a potent small molecule inhibitor of Dihydroorotate dehydrogenase (DHODH), demonstrating an EC50 of 16 nM against multidrug-resistant Plasmodium falciparum in vitro. It serves as a valuable chemical probe for studying malaria parasite biology and for antimalarial drug discovery research.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2057420-29-6
• MW: 485.42
• Formula: C₂₃H₂₁F₆N₃O₂
• SMILES: C(#N)[C@@H]1[C@@H]([C@@H](CO)N1C(NCCC)=O)C2=CC=C(C=C2)C3=CC(C(F)(F)F)=C(C(F)(F)F)C=C3
• Target: Parasite,DNA/RNA Synthesis,Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121596187