BRD4 degrader AT1

SKU: orb1689886

Description

AT1 is a potent and selective PROTAC degrader of BRD4, exhibiting a cellular Kd of 44 nM for the BD2 domain. This tool compound is widely used in vitro and in vivo to investigate BRD4 biology, epigenetic signaling, and oncology research.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2098836-45-2
• MW: 972.68
• Formula: C₄₈H₅₈ClN₉O₅S₃
• SMILES: CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCCCCCSC(C)(C)[C@@H](C(=O)N4C[C@@H](C[C@H]4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)NC(=O)C)C7=CC=C(C=C7)Cl)C
• Target: PROTACs,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124201841