BRD 4354 ditrifluoroacetate

SKU: orb2279536

Description

BRD 4354 ditrifluoroacetate is a selective class IIa histone deacetylase (HDAC) inhibitor, demonstrating moderate potency against HDAC5 and HDAC9 with IC50 values of 0.85 µM and 1.88 µM, respectively. This compound is a valuable chemical probe for epigenetic research, utilized in both in vitro and in vivo studies to investigate the roles of HDAC5/9 in cardiac development, neuronal function, and muscle differentiation.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• MW: 610.93
• Formula: C₂₅H₂₅ClF₆N₄O₅
• SMILES: OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138454746