BRD 4354 ditrifluoroacetate

SKU: orb2279536

Description

BRD 4354 ditrifluoroacetate is a selective class IIa histone deacetylase (HDAC) inhibitor, demonstrating moderate potency against HDAC5 and HDAC9 with IC50 values of 0.85 µM and 1.88 µM, respectively. This compound is a valuable chemical probe for epigenetic research, utilized in both in vitro and in vivo studies to investigate the roles of HDAC5/9 in cardiac development, neuronal function, and muscle differentiation.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

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Key Properties

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MW	610.93
Formula	C₂₅H₂₅ClF₆N₄O₅
SMILES	OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Target	HDAC

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

138454746 ↗

Key Properties

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No computed properties available.

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