Boc-NH-PEG11-OH

SKU: orb1307496

Description

Boc-NH-PEG11-OH is a heterobifunctional polyethylene glycol linker designed for constructing PROTAC molecules. Its structure facilitates the conjugation of a target-binding ligand to an E3 ubiquitin ligase recruiter, enabling the targeted degradation of proteins in both cellular and biochemical research applications.

Research Area

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1556847-53-0
• MW: 601.72
• Purity: 98.08% (May vary between batches)
• Formula: C₂₇H₅₅NO₁₃
• SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCOCCO)OCCNC(OC(C)(C)C)=O
• Target: PROTAC Linker

Bioactivity

• In Vitro:
  PROTACs consist of two distinct ligands linked together: one binding to an E3 ubiquitin ligase and the other to a target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PROTACLinker, PROTAC Linkers, PROTAC Linker, PEGs, Inhibitor, inhibit, Boc NH PEG11 OH, BocNHPEG11OH, Boc-NH-PEG-11-OH, Boc-NH-PEG11-OH

Compound Identifiers

PubChem CID

126480541