BMS-986470

SKU: orb3134906

Description

BMS-986470 is a CRBN E3 ubiquitin ligase modulator (CELMoD) that activates fetal hemoglobin (HbF). It is an orally available molecular glue degradator targeting ZBTB7A and WIZ protein degradation, thereby inducing gamma globin synthesis and activating HbF. It is applicable for studying sickle cell disease (SCD).

Key Properties

• CAS Number: 3036554-12-5
• MW: 523.54
• Formula: C₂₉H₂₅N₅O₅
• SMILES: N(C1=C2C(C(=O)N(C2=O)[C@@H]3C(=O)NC(=O)CC3)=CC=C1)C4=C(C=C5C(=C4)N(C)C(=O)CC5)C=6C=C(C)N=CC6
• Target: PROTACs,Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTACs,Molecular Glues