Blixeprodil

SKU: orb3028533

Description

Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2881017-49-6
• MW: 221.271
• Formula: C₁₃H₁₆FNO
• SMILES: N(C)[C@@]1(C(=O)CCCC1)C2=CC=C(F)C=C2
• Target: iGluR

Storage & Handling

• Storage: Powder: -20°C for 3 years. In solvent: -80°C for 1 year.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GM-1020

Structure

Quick Database Links

Gene Symbol

iGluR