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Catalog Number | orb1303248 |
---|---|
Category | Small Molecules |
Description | Bisantrene |
Purity | 98.57% |
MW | 398.46 |
Biological Activity | Bisantrene (CL216942) is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. |
CAS Number | [78186-34-2] |
Formula | C22H22N8 |
SMILES | C1CN=C(N\N=C\c2c3ccccc3c(\C=N\NC3=NCCN3)c3ccccc23)N1 |
Storage | -20°C |
Note | For research use only |