Bisantrene

SKU: orb1303248

Description

Bisantrene (CL216942) is an anthracenyl bishydrazone antineoplastic agent that intercalates DNA, causing strand breaks and inhibiting replication. It exhibits activity comparable to doxorubicin without associated cardiotoxicity. This compound has been utilized in research on various cancers in both in vitro and in vivo experimental models.

Research Area

Molecular Biology

Key Properties

• CAS Number: 78186-34-2
• MW: 398.46
• Purity: 98.57% (May vary between batches)
• Formula: C₂₂H₂₂N₈
• SMILES: C1CN=C(N\N=C\c2c3ccccc3c(\C=N\NC3=NCCN3)c3ccccc23)N1
• Target: Topoisomerase
• Solubility: H2O:0.1 mg/mL (0.25 mM);DMSO:1 mg/mL (2.51 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL-216942, CL216942, CL 216942, Bisantrene, Inhibitor, inhibit, Topoisomerase

Compound Identifiers

PubChem CID

5351322