Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)

SKU: orb1984859

Description

This compound is a biotinylated, PEG-based linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It serves as a critical spacer to connect target protein ligands to E3 ubiquitin ligase ligands, enabling the development of degraders for both in vitro and in vivo target validation studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1205744-09-7
• MW: 689.95
• Formula: C₃₃H₆₃N₅O₈S
• SMILES: CCN(C(C)C)C(C)C.[H][C@]12CS[C@@H](CCCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC(O)=O)[C@@]1([H])NC(=O)N2
• Target: Others,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118989702