Betamipron

SKU: orb1308647

Description

Betamipron (CS-443) is a nephroprotective agent co-administered with the carbapenem antibiotic panipenem. It functions by competitively inhibiting the renal tubular uptake of panipenem, thereby reducing its nephrotoxic potential. This combination is utilized in research models to study antibiotic-induced kidney injury and protective pharmacological strategies.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 3440-28-6
• MW: 193.2
• Purity: 99.91%
• Formula: C₁₀H₁₁NO₃
• SMILES: OC(=O)CCNC(=O)C1=CC=CC=C1
• Target: Antibacterial,Antibiotic
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.35 mM);Ethanol:37 mg/mL (191.51 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:50 mg/mL (258.8 mM)

Bioactivity

• In Vivo:
  Panipenem is a non-intestinal carbapenem-class antibiotic that demonstrates antimicrobial activity against both Gram-negative/positive aerobic bacteria and anaerobic bacteria, including Streptococcus pneumoniae and species producing β-lactamase.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, N-Benzoyl-b-alanine, N-Benzoyl-beta-alanine, N-Benzoyl-β-alanine, CS 443, CS443, CS-443, Antibiotic, Bacterial, Betamipron

Compound Identifiers

PubChem CID

71651