Besifloxacin Hydrochloride

SKU: orb1300796

Description

Besifloxacin hydrochloride, known under the research code BOL-303224-A, is a fourth-generation fluoroquinolone antimicrobial agent. It is utilized in research for investigating its potent activity against bacterial pathogens in both in vitro susceptibility assays and in vivo infection model studies.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 405165-61-9
• MW: 430.3
• Purity: 99.95% (May vary between batches)
• Formula: C₁₉H₂₁ClFN₃O₃·HCl
• SMILES: C1CCN(C[C@@H](C1)N)c1c(cc2c(c1Cl)n(cc(c2=O)C(=O)O)C1CC1)F.Cl
• Target: Antibacterial,Topoisomerase,Antibiotic,DNA/RNA Synthesis
• Solubility: DMSO:11 mg/mL (25.56 mM)

Bioactivity

• In Vitro:
  Besifloxacin has effectively bactericidal activity against prevalent and drug-resistant pathogens. Besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is particularly notable against gram-positive and gram-negative isolates that are resistant to other fluoroquinolones and classes of antibacterial agents.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Besifloxacin, Besifloxacin HCl, Besifloxacin Hydrochloride, Besivance hydrochloride, Besivance Hydrochloride, Antibiotic, Bacterial, BOL-303224-A

Compound Identifiers

PubChem CID

10224595