Bergamottin

SKU: orb1301329

Description

Bergamottin (5-Geranoxypsoralen) is a bioactive furanocoumarin shown to enhance glucose tolerance and insulin sensitivity in KK-A^y diabetic mouse models. It is utilized in metabolic disease research, particularly for studying antidiabetic mechanisms in vivo and related molecular pathways in vitro.

Research Area

Metabolism Research

Key Properties

• CAS Number: 7380-40-7
• MW: 338.40
• Purity: 99.95%
• Formula: C₂₁H₂₂O₄
• SMILES: CC(C)=CCC\C(C)=C\COc1c2ccoc2cc2oc(=O)ccc12
• Target: Cytochromes P450
• Solubility: DMSO:65.00 mg/mL (192.08 mM);10% DMSO+90% Corn Oil:2.50 mg/mL (7.39 mM)

Bioactivity

• Target IC50:
  CYP2B2:4.535 μM|CYP1A1:10.703 nM(Ki)|CYP1A1:0.192 μM|CYP1A2:5.077 μM|CYP2B1:9.495 μM

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5-Geranoxypsoralen, Cytochrome P450, CYPs, CYP1A1, Bergamotine, Bergamottin, Bergaptin, Inhibitor, inhibit

Compound Identifiers

PubChem CID

5471349