Benproperine phosphate

SKU: orb1221308

Description

Benproperine phosphate is a cough suppressant.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 19428-14-9
• MW: 407.44
• Purity: >98% (HPLC)
• Formula: C₂₁H₃₀NO₅P
• SMILES: OP(O)(O)=O.CC(COc1ccccc1Cc1ccccc1)N1CCCCC1
• Target: Others
• Solubility: DMSO:60mg/mL;Water:81mg/mL; Alcohol:3mg/mL

Bioactivity

• In Vivo:
  Animal model: Female BALB/c nude mice of 6-week-old with AsPC-1 cells. Dosage: 50, 100 mg/kg. Administration: Oral gavage; 5 days per week for 4 weeks. Result: Inhibited primary pancreatic tumor growth compared to the vehicle control (47.7% inhibition) without body weights change.
• In Vitro:
  Cell Viability Assay Cell line: DLD-1, AsPC-1, CFPAC-1, A375P, A375P, MDA-MB-231, DU145, DU145 cancer cells. Concentration: 20, 40, 60, 80, 100, 120 μM. Incubation time: For 24 hours. Result: Inhibited cell viability in a dose-dependent manner.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Blascorid | Pirexyl phosphate

Quick Database Links

Gene Symbol

Others