BCX 1470 methanesulfonate

SKU: orb1708046

Description

BCX 1470 methanesulfonate is a potent and selective inhibitor of the serine proteases factor D and C1s, with IC50 values of 96 nM and 1.6 nM, respectively. It demonstrates significantly greater potency against these complement system enzymes than against trypsin. This inhibitor is a valuable research tool for studying the classical and alternative complement pathways in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Protein Biochemistry

Key Properties

• CAS Number: 217099-44-0
• MW: 398.48
• Formula: C₁₅H₁₄N₂O₅S₃
• SMILES: CS(O)(=O)=O.NC(=N)c1cc2ccc(OC(=O)c3cccs3)cc2s1
• Target: Complement System,Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9822204