BChE/HDAC6-IN-1

SKU: orb1944443

Description

BChE/HDAC6-IN-1 is a potent and selective dual inhibitor of BChE (IC50 = 4 nM) and HDAC6 (IC50 = 8.9 nM). It has demonstrated in vivo efficacy by alleviating cognitive deficits in an Aβ1–42-induced mouse model, highlighting its utility for Alzheimer's disease research in both cellular and animal studies.

Research Area

Epigenetics & Chromatin, Molecular Biology, Neuroscience

Key Properties

• CAS Number: 2925457-27-6
• MW: 601.74
• Formula: C₃₄H₄₃N₅O₅
• SMILES: C(N(CC)CC)C1=C(CNC(=O)C2=CC(NC(=O)C3=CC(NC(CCCCCCC(NO)=O)=O)=CC=C3)=CC=C2)C=CC=C1
• Target: HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510547