BAY-677

SKU: orb1710315

Description

BAY-678 is a potent, selective, and orally bioavailable inhibitor of human neutrophil elastase (HNE) with an IC50 of 20 nM, designated as a chemical probe by the SGC. It serves as a key tool for investigating HNE's role in inflammatory and respiratory diseases in both cellular and animal models.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 2117404-84-7
• MW: 400.35
• Formula: C₂₀H₁₅F₃N₄O₂
• SMILES: CC(=O)C1=C(C)N(C(=O)N[C@H]1c1ccc(nc1)C#N)c1cccc(c1)C(F)(F)F
• Target: Others,Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

68944900