Banoxantrone-d12 dihydrochloride

SKU: orb1706261

Description

Banoxantrone D12 dihydrochloride is a deuterated version of the bioreductive prodrug Banoxantrone (AQ4N). Under hypoxic conditions, it is enzymatically reduced to its active form, AQ4, a potent topoisomerase II inhibitor that binds DNA. This labeled compound is used in pharmacokinetic and metabolic studies in cancer research, both in vitro and in vivo.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 1562066-98-1
• MW: 529.48
• Formula: C₂₂H₃₀Cl₂N₄O₆
• SMILES: Cl.Cl.[2H]C([2H])([2H])N(=O)(CCNc1ccc(NCCN(=O)(C([2H])([2H])[2H])C([2H])([2H])[2H])c2C(=O)c3c(O)ccc(O)c3C(=O)c12)C([2H])([2H])[2H]
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

72792477