Bamocaftor

SKU: orb1698201

Description

Bamocaftor is a small molecule corrector targeting the F508del-CFTR mutation in cystic fibrosis, designed to restore protein function. It is used in research, often in combination with agents like tezacaftor, for in vitro and in vivo studies investigating CFTR channel rescue and therapeutic strategies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2204245-48-5
• MW: 591.65
• Purity: 99.93% (May vary between batches)
• Formula: C₂₈H₃₂F₃N₅O₄S
• SMILES: C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccccc2)-n2ccc(OCCC3(CC3)C(F)(F)F)n2)C(C)(C)C1
• Target: CFTR
• Solubility: DMSO:18.33 mg/mL (30.98 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VX659, VX-659, VX 659, F508del-CFTR, Bamocaftor

Compound Identifiers

PubChem CID

134393443