Bafilomycin A1

• Catalog Number: orb1300510
• Category: Small Molecules
• Description: Bafilomycin A1
• CAS Number: 88899-55-2
• Purity: 98.38%
• MW: 622.83
• SMILES: [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C\[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C
• Formula: C₃₅H₅₈O₉
• Biological Activity: Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.