Bacopaside I

SKU: orb1684745

Description

Bacopaside I, a saponin from Bacopa monniera, functions as an Aquaporin-1 channel modulator with neuroprotective properties. It has demonstrated anti-Alzheimer's potential in APP/PS1 mouse models by promoting amyloid-β clearance and exhibits antioxidant, free radical scavenging, and antidepressant-like activities in research studies.

Key Properties

• CAS Number: 382148-47-2
• MW: 979.13
• Purity: 98.66%
• Formula: C₄₆H₇₄O₂₀S
• SMILES: CC(C)=C[C@@H]1CO[C@]23C[C@]4(CO2)[C@H](CC[C@@H]2[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O[C@@H]7O[C@H](COS(O)(=O)=O)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]6O[C@@H](CO)[C@H](O)[C@H]6O)C(C)(C)[C@@H]5CC[C@@]42C)[C@H]3[C@@]1(C)O
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.04 mM);DMSO:22.5 mg/mL (22.98 mM)

Bioactivity

• Target IC50:
  COX-1:16.17 μM|COX-2:7.76 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cAMP, Bacopaside I, GABA, NMDAR, Inhibitor, inhibit

Compound Identifiers

PubChem CID

21599442