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AZD0233

SKU: orb3134908

Description

AZD0233 is an orally active CX3CR1 antagonist that immunomodulates the CX3CR1/CX3CL1 signaling axis. It improves cardiac function in dilated cardiomyopathy mouse models while reducing macrophage infiltration and fibrotic scarring.

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Key Properties

CAS Number3036141-78-0
MW456.54
FormulaC19H29FN6O4S
SMILESC([C@@H](C)C=1C(F)=CC(OC)=NC1)C=2N=C(N[C@H](CC(C)C)CO)N=C(NS(C)(=O)=O)N2
TargetCXCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

AZD0233 (orb3134908)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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