AZD-1236

SKU: orb1740250

Description

AZD1236 is a selective, potent inhibitor of human MMP-9 and MMP-12, demonstrating significant anti-inflammatory effects in preclinical models of lung injury. It has been shown to reduce hemorrhage and macrophage infiltration in rodent models of tobacco smoke exposure and MMP-12 instillation, supporting its research application in studying chronic obstructive pulmonary disease (COPD) and acute lung injury pathways.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 459814-89-2
• MW: 402.85
• Formula: C₁₅H₁₉ClN₄O₅S
• SMILES: S(C[C@@]1(C)NC(=O)NC1=O)(=O)(=O)N2CCC(OC3=CC=C(Cl)C=N3)CC2
• Target: Others,MMP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24751752