AWZ1066S

SKU: orb1309960

Description

AWZ1066S is a potent and selective anti-Wolbachia agent, demonstrating an EC50 of 2.5 nM in cellular assays. It is a promising candidate for abbreviated filariasis treatment regimens, with research applications in both in vitro mechanistic studies and in vivo animal models of filarial infection.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2239272-16-1
• MW: 404.39
• Purity: 98.32%
• Formula: C₁₉H₁₉F₃N₆O
• SMILES: C[C@H]1COCCN1c1nc(NCc2cccnc2C(F)(F)F)c2cccnc2n1
• Target: Parasite
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.89 mM);DMSO:120 mg/mL (296.74 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CYP3A4, CYP2C9, AWZ1066S, AWZ-1066S, anti-Wolbachia, Inhibitor, inhibit, lymphatic filariasis (elephantiasis), Onchocerciasis (river blindness), oral, Parasite, tropical diseases

Compound Identifiers

PubChem CID

135240137