ATP synthase inhibitor 1

SKU: orb1309967

Description

ATP synthase inhibitor 1 specifically targets the c-subunit of the mitochondrial F1/FO-ATP synthase. This action blocks the mitochondrial permeability transition pore (mPTP) opening without depleting cellular ATP, making it a valuable tool for studying ischemia-reperfusion injury, apoptosis, and cardiomyocyte protection in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1023043-30-2
• MW: 411.93
• Purity: 99.83% (May vary between batches)
• Formula: C₁₇H₁₈ClN₃O₃S₂
• SMILES: Clc1ccc(s1)S(=O)(=O)N1CCC2(CC1)N(CNC2=O)c1ccccc1
• Target: ATPase
• Solubility: DMSO:4.94 mg/mL (11.99 mM)

Bioactivity

• In Vitro:
  ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex.

Storage & Handling

• Storage: Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

F0F1 ATP synthase, F1/FO-ATP synthase, Inhibitor, inhibit, ATP Synthase, ATP synthase inhibitor 1, ATP synthase inhibitor1, ATP synthase inhibitor-1

Compound Identifiers

PubChem CID

3782788