AS2863619 free base

SKU: orb1710381

Description

AS2863619 free base is a potent, orally bioavailable inhibitor of CDK8 and CDK19 that promotes the differentiation of antigen-specific T cells into Foxp3+ regulatory T cells. This conversion is mediated through enhanced STAT5 activation and subsequent Foxp3 gene induction, making it a valuable tool for studying immune tolerance in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	2241300-50-3
MW	332.32
Formula	C₁₆H₁₂N₈O
SMILES	Cc1nc2ccc(cc2[nH]1)-n1c(nc2cnccc12)-c1nonc1N
Target	STAT,CDK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

139600292 ↗

Key Properties

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No computed properties available.

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