ARN23765

SKU: orb2945060

Description

ARN23765 is a potent F508del-CFTR corrector (EC50 = 38 pM) that rescues mutant protein maturation and membrane function. It is a valuable research tool for investigating CFTR pharmacology and cystic fibrosis disease mechanisms in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2244458-40-8
• MW: 615.504
• Formula: C₃₀H₂₂F₅N₃O₆
• SMILES: O([C@@H]1C=2N(N=C(C(F)(F)F)C2CCC1)C3=CC(C(N(C)C=4C=C5C(=CC4)OC(F)(F)O5)=O)=CC=C3)C6=CC=C(C(O)=O)C=C6
• Target: CFTR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

142428878