AR-H067637

SKU: orb1701174

Description

AR-H067637 is a potent, competitive thrombin inhibitor (K(i) = 2-4 nM) effective against both free and clot-bound thrombin. It inhibits thrombin generation in plasma (IC(50) 0.6 µM) and potently blocks thrombin-induced platelet activation and aggregation. This inhibitor is a valuable tool for studying thrombosis and hemostasis in biochemical, plasma-based, and cellular assays.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 433937-74-7
• MW: 466.87
• Formula: C₂₁H₂₁ClF₂N₄O₄
• SMILES: C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)(=O)N2[C@H](C(NCC3=CC=C(C(=N)N)C=C3)=O)CC2
• Target: Thrombin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9811290