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Apremilast-d5

SKU: orb1992949

Description

Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α release by lipopolysaccharide (IC50: 104 nM).

Images & Validation

Key Properties

CAS Number1258597-47-5
MW465.53
FormulaC22H24N2O7S
SMILES[2H]C([2H])([2H])C([2H])([2H])Oc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O
TargetPDE,TNF,Apoptosis

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Apremilast-d5 (orb1992949)

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