Apoptosis,Others Antibody

SKU: orb3032160

Description

VGL101 is a human IgG1 monoclonal antibody (mAb) that targets TREM-2. It acts as a pSYK agonist with an EC50 of 0.77 nM. Under ALSP pathological conditions, VGL101 enhances the survival of microglia and monocyte-derived macrophages, inhibits apoptosis, and aids in restoring cell morphology to resemble the normal activated CSF1R state. It is applicable in leukoencephalopathy research. Recommended isotype control: Human IgG1 kappa, Isotype Control.

Research Area

Cell Biology

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	Apoptosis,Others
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Apoptosis,Others

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