Apomine

SKU: orb1305197

Description

Apomine (SR-9223i) is a small molecule that induces apoptosis in myeloma cells in vitro and shows in vivo regulatory activity. It functions by accelerating HMG-CoA reductase degradation and stimulating LDL receptor activity. This compound also synergistically enhances the anti-myeloma effects of statins like lovastatin in research settings.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 126411-13-0
• MW: 562.66
• Purity: >99.99% (May vary between batches)
• Formula: C₂₈H₅₂O₇P₂
• SMILES: P(C(P(OC(C)C)(OC(C)C)=O)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(OC(C)C)(OC(C)C)=O
• Target: HMG-CoA Reductase,Apoptosis
• Solubility: 10% DMSO+90% Corn Oil:1.5 mg/mL (2.67 mM);DMSO:15 mg/mL (26.66 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SK&F99085, SK&F-99085, SK&F99085, SK&F-99085, SK&F 99085, SK&F 99085, SR-45023A, SR-9223i, Apomine, APB-231-A2, APB-231-A-2, HMG-CoA reductase, HMGCoA Reductase, HMGCoAReductase

Compound Identifiers

PubChem CID

176405